Isolation of Microcystins from the Cyanobacterium Planktothrix rubescens Strain No80

M. Muehlberg; K.D. Siebertz; B. Schlegel; P. Schmieder; C. Hackenberger*

Chem. Commun. 50, 4603 - 4606 (2014)

The thioacid–azide reaction and its chemoselectivity were probed with alkyl azides for a potential application to form amide bonds in aqueous solvents. Our results reveal that under acidic conditions thioamides were formed as major reaction products suggesting a competing mechanism, whereas reactions forming amides predominated at slightly higher pH values.